Cleanance

Comedomed+ Intensive Anti-Blemish Care

Cleanance

Comedomed+ Intensive Anti-Blemish Care

Hydrates - Aids the disappearance of blackheads - Corrects imperfections - Regulates sebum - Reduces residual marks

A lightweight, non-comedogenic gel moisturiser for acne-prone skin. Visible results from as early as 5 hours¹ and clinically proven to help target pimples and blackheads for clearer-looking skin in just 15 days³. Formulated with 25% Comedoclastin™ and 4% Niacinamide, it regulates excess oil, unclogs pores, soothes visible redness, and refines skin texture. Ideal for oily and combination skin, use morning and evening or as targeted care for a smooth, matte finish.

  • An Avene innovation tested on over 4600 patients with a 1-year anti-relapse efficacy*.
  • Targets existing and future blemishes & breakouts by regulating excess sebum production.

Usable by Teenagers - Adults

Skin type Acne-prone skin - Skin with blemishes

Need Anti-blemishes - Reduce residual marks - Anti recurrence

Made in France

Say goodbye to stubborn breakouts and hello to confidence with Avène Cleanance Comedomed+ Intensive Blemish Care, the ultimate moisturiser for acne-prone skin. Visible results from as early as 5 hours¹, this lightweight gel moisturiser is clinically proven to help target oily skin that may be congested with blackheads and existing pimples whilst helping prevent new ones from forming for a clearer-looking skin in just 15 days³.

Formulated with 25% Comedoclastin™, a patented plant-based ingredient derived from milk thistle, it helps regulate sebum hyperproduction, unclog pores and prevent the formation of blackheads and blemishes. 4% Niacinamide helps soothe visible redness, refine the appearance of pores and post-acne marks, and support the skin barrier.

Unlike heavy creams that clog pores, this non-comedogenic gel moisturiser absorbs quickly, feels fresh, and won’t leave your skin greasy. Ideal for oily and combination skin, use as a moisturiser in the morning and evening or as targeted care. Whether you’re dealing with breakouts now or want to keep them away, this matte moisturiser is your go-to for clear, balanced skin.

A few words from our expert

Microcomedo expertise in a unique innovation for quick and long-lasting results on all visible and invisible imperfections.

Benefits

• Visible results from 5 hours¹
• - 50% blemishes, blackheads and marks in 1 month²
• A fresh gel moisturiser for oily, acne-prone skin which helps reduce appearance of pimples and blackheads
• Use as a day or night moisturiser or on targeted localised areas
• Minimalist formula, including exclusive Comedoclastin™ from milk thistle, and Niacinamide to soothe visible redness, refine pores, and support the skin barrier.
• Very rich in our Thermal Spring Water to soothe and soften
• Non-comedogenic, dermatologist-tested formula that won’t clog pores

¹ Use test, 73 consumers, from the 1st application.
² Clinical rating, 35 subjects with 2 applications per day for 2 months. Results after 28 days of use.
³ Clinical rating, 35 subjects with 2 applications per day for 2 months. Results vs baseline after 15 days of use.
⁴ vs untreated skin. Instrumental test on 33 subjects after a single application.

*Limits the reappearance of imperfections. Clinical scoring, 2 applications per day for 12 months, 51 subjects.

*Limits the reappearance of imperfections. Clinical scoring, 2 applications per day for 12 months, 51 subjects.
***Use test, 73 consumers, from 1st application.
****Clinical scoring, 39 subjects with 2 applications per day for 2 months. Results after 14 days of use.
*****Instrumental test on 33 subjects.

Green impact index: C

Environmental impact

Formuła

Note Formuła : C

Biodegradable formula*
Formulated to limit the impact on the aquatic environment**
*According to an OECD 301 test or biodegradability index method
**According to an OECD 301 test and CLP classification of the formula

Packaging

Note Packaging : E

Manufacturing

Note Manufacturing : A

Manufactured and conditioned in an eco-friendly certified factory*
Cold-made formula without the use of heat
*According to ISO 14001 and/or 50001

Transport

Note Transport : C

Product manufactured and packaged on sites located less than 1,000 km apart

Societal impact

Societal impact

Note Societal impact : A

Product manufactured and packaged in a factory in France with high social standards
Avène is a brand of the Pierre Fabre Group, certified at the highest Exemplary level of AFNOR Certification’s ‘Committed to CSR’ and ‘Responsibility Europe’ labels, thus consolidating a long-standing commitment to sustainable development.
Product contains no ingredients derived from animals

Our commitments

Application

Frequency of use

2 times a day

Apply morning and evening to the face, torso and back after cleansing with Cleanance Cleansing Gel. Can be used alone or alongside medicinal acne treatments (should not be used with oral isotretinoin). Suitable for teenagers from 9 years old and adults. Suitable for daily use.
The product odour is related to its innovative ingredient and will quickly disappear after application. Avoid contact with eyes. Excellent skin tolerance.

Ingredients

AVENE THERMAL SPRING WATER (AVENE AQUA). ISOPROPYL ALCOHOL. PEG-6. GLYCERIN. NIACINAMIDE. SILYBUM MARIANUM FRUIT EXTRACT. SILICA. POLYACRYLATE-13. POLYISOBUTENE. POLYSORBATE 20. SORBITAN ISOSTEARATE. WATER (AQUA)

The consumer is advised to systematically check the composition of the product before purchasing it.

Niacinamide

Niacinamide

 Improves the appearance of pores and reduces post-acne marks for an overal enhanced action to reduce imperfections.
Comedoclastin™

Comedoclastin™

Helps to reduce the appearance of blemishes and limits their reappearance.

Results

• Visible results from 5 hours¹
• - 50% blemishes, blackheads and marks in 1 month²
• - 39% blemishes from 15 days³
• - 54% blackheads from 15 days³
• - 43% post-acne marks from 15 days³
• +81% hydration 1 hour after application⁴
• 24 hours of long-lasting hydration⁴

    ¹ Use test, 73 consumers, from the 1st application.
    ² Clinical rating, 35 subjects with 2 applications per day for 2 months. Results after 28 days of use.
    ³ Clinical rating, 35 subjects with 2 applications per day for 2 months. Results vs baseline after 15 days of use.
    ⁴ vs untreated skin. Instrumental test on 33 subjects after a single application.

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