Cleanance Comedomed


Reduces blemishes - Reduces excess sebum - Tightens pores

Avène Cleanance Comedomed is a highly concentrated, fast-acting formula providing long-lasting clinical benefits, and has a targeted dual action:
1. Effectively reduces and limits the reappearance of blemishes and blackheads
2. Regulates the hyperproduction of sebum

  • Action rapide
  • Anti-récidive***
  • High tolerance
  • Fragrance-free

Significantly reduces blemishes and blackheads from 7 days*

Acne-fighting, anti-blemishes, anti-recurrence

Pump bottle

Usable by Pregnant women - Young mothers - Teenagers - Adults

Age From 12 year(s)

Skin type Acne-prone skin

Need Anti-blemishes - Anti recurrence

Made in France


Helping you reduce blemishes and blackheads once and for all

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Frequency of use

2 times a day

Tips for use

Dispense 1 dose of Cleanance Comedomed on your fingertips.
• Start by dabbing it onto the T-zone and the cheeks.
• Use circular motions to boost penetration.
• Finish by smoothing on the cheeks and lower face.
Reapply morning and evening.

An expert tip

The 2 essential steps to take care of your acne-prone skin!
Our one piece of advice:
• Rigorously yet gently remove make-up and cleanse the face, both morning and evening!
• Also apply an anti-blemish product morning and evening.

Clinical results
Clinical results

Effective for oily or acne-prone skin type

7 days smooth skin texture within 7 days¹
90% 90% clearer skin²
45%reduced blemishes by -45% after 2 months³,

¹Clinical assessment by dermatologist conducted on 51 subjects – Comedomed applied twice daily.
²Comparative study conducted on 36 subjects (aged 18-34) under dermatological control for 56 days. One untreated control group (N=18), one group treated twice a day with Cleanance Comedomed (N=18)
³% of satisfaction – User test on 51 subjects – Comedomed applied twice daily

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Your reviews on  Cleanance Comedomed

Your reviews on Cleanance Comedomed

Tell us what you think, your opinion is very important for us.


would recommend this product to a friend

Opinion 1 on 71
genuinely life changing!

I am 20 now, but have suffered with horrible acne since ages 14. my older brother also had horrible acne, and due to this saw many a doctor and dermatologist, got multiple medical creams etc; so due to this when it came to my acne my mother had already been through it all with my brother so i tried all the same "acne clearing products" you could imagine. Nothing, and i mean NOTHING was helping my skin. Due to large amounts of breakouts, especially on my cheeks, i was left (and still am to this day)with lots of acne scarring and enlarged pores. so trying to fight live acne+acne scars at once was a hard battle. Until one day when i was 17 my mum brought home the Avene Facial Cleanser in a starter kit which came with a small tube of the Clearance Condemed + another product i forget the name. This acne gel is the only thing i have found to fight acne efficiently. Its fast acting (i mean you can see the difference after one day), not harsh (i have sensistive skin), and buildable but not a lot of product is necessary. Yes, it does have a smell but its not horrendous (IMO) and definitely more tolerable than a lot of other scents (plus once its on your face it pretty much vanishes anyway). I swear by this product to treat acne, and i wish i had found it first go when i was 14. (to treat my acne scars i use Bio Oil, not Avene branded)

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Miracle product changed my skin during pregnancy

I have been using this little baby during my whole 9 months of pregnancy. When I found out I was pregnant my skin became very erratic and was breaking out severely. I could no longer use my preion medication as it wasn't safe for pregnancy. I was on the hunt for a alternative treatment. I'm no stranger to Avene. I have been using for many years. I already use the thermal spring water daily in my skincare routine and has never let me down. During a sale I picked this up in order to help my skin. Within days the redness had gone and breakouts were non existent. I have been using twice daily and it has been amazing. It's so gentle but yet effective. I'm due to give birth any day and I don't think I will go back to my preion medication as this has worked so well for me and definitely not as harsh and no side effects. Love this product #AveneReview

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Life changing

Avene Comedomed has change my skin remarkably for the better. I no longer wake up in the morning to find another pimple on my face, especially from roseacea. Blackheads no longer form on my nose by the end of the day, same with open pores and oily T-zone. It's such a relief. I've tried so many other more expensive products but this does the job completely, My skincare routine now revolves around this product as I transfer over to a complete Avene routine. I wish it was available when I was a teenager. I would like to buy this in a larger quantity as I'll never be without it!

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Efficient clean product

Great product and perfect timing to try it. my skin has changed after having a baby. It is dehydrated but still oily. This product has done wonders for my skin. It keeps my skin smooth and clean.

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Effective value product

Avene Cleanance Comedomed is easy to use. its texture feels nice on my skin - not too thick like a cream and not to gel-like. I like that it has Avene thermal spring water as one of the ingredients. overall, Cleanance Comedomed helped me reduced my pimple and blemishes, especially during certain time of the month. my skin didn't look shiny part way through the day. the only negative I had was that my skin feels a bit dry a night, so I ended up putting extra moisturizer on top of Cleanance Comedomed (which could be due to the harsh winter months?)

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Ingredients Ingredients

A combination of innovative key ingredients selected for their effectiveness on sensitive oily or acne-prone skin.


The consumer is advised to systematically check the composition of the product before purchasing it.

Avène Thermal Spring Water


Clinically proven by 150 studies to soothe, soften and calm the skin.



Helps to reduce the appearance of blemishes and limits their reappearance.


Any concerns or questions? Our experts are here for you.

Rest assured, Cleanance Comedomed does not contain any endocrine disruptors.

The smell is linked to the key ingredient Comedoclastin™ (milk thistle extract), which is present in the product. But rest assured, the product is fragrance free. This odour evaporates quickly and does not interfere with the tolerance of the product and does not present any risk to the skin. It has been proven that skin tolerates Cleanance Comedomed extremely well.

Yes, when starting a new acne-prone skincare routine (whether a medicine or dermo-cosmetic) can act as a trigger for a breakout. Under its effect, a large number of pimples, previously dormant under the skin, emerge at the same time. This causes the phenomenon of a "flare-up" (an explosion or exacerbation of pimples). Continue to use your product, because the next phase will allow for the exhaustion of the "embryo stock” of pimples. This will help to keep blemishes to a minimum.
In case of discomfort, use can be reduced to once a day.

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